Immuno-oncology studies

Our services deliver quantification of the various lymphocytes populations and inflammatory cells within the tumor tissue. Quantifying changes in numbers of specific cell types can help confirm the mechanism of action of immunotherapies. Furthermore, co-localization of markers of cell activation can further characterize therapeutic response in terms of the functional status of sub-type lineage of immune/inflammatory cells within the tumor microenvironment. 

Bluewave Bio is able to further quantify immune cell relationships in terms of cell infiltrations at tumor/stroma margins. Using advanced image analysis software, we can quantify immune cells within pre-defined distances inside or outside the tumor border. This can be used to assess the mechanism of action of therapies that are designed to modulate cell infiltration. 

Bluewave Bio can interrogate the tumor microenvironment in terms of spatial relationships between interacting cells. This approach can help confirm the mechanism of action of therapies that are designed to enhance or reduce the interaction between specific cell types within the tumor tissue. 

Bluewave Bio has a group of experts in development of algorithms to identify different tissue morphologies based on their color, texture, and contextual features. We provide detailed and informative data on tumor morphology, eliminating the need for manual annotations. 

Our services generate large amounts of data that are intended to provide deeper insights into the tumor microenvironment. A group of experienced pathologists and data scientists will run sophisticated bioinformatics analysis pipeline to maximize the value out of your data.